Stem cell-based therapies for vascular regeneration in peripheral artery diseases David Smadia and Jean-Sebastien Silvestre 18. Everyone interested in the future of personalized medicine and nutrition or agriculture, as well as researchers in academia, government and industry will find this publication of the utmost interest for their work. Micrornas In Toxicology And Medicine Sahu Saura C can be very useful guide, and micrornas in toxicology and medicine sahu saura c play an important role in your products. Important considerations in the therapeutic application of stem cells in bone healing and regeneration Hoda Elkhenany, Shawn Bourdo, Alexandru Biris, David Anderson and Madhu Dhar 24. In addition to scientific studies, the challenges and opportunities facing governments, academia and the industry are included. The Effect of Human Pluripotent Stem Cell Platforms on Preclinical Drug Development Kevin G. Category: Medical Author : Artemis P.
Each chapter contains several references to current literature and important resources for further reading. Unites world-leading experts to present cutting-edge, agent-specific information on chemical warfare agents and their adverse effects on human and animal health and the environment. Disease-Specific Stem Cell Models for Toxicological Screenings and Drug Development Matthias Jung, Juliane-Susanne Jung, Jovita Schiller and Insa S. The editors have built Issues in National, Regional, and Environmental Health and Medicine: 2011 Edition on the vast information databases of ScholarlyNews. Human pluripotent stem cells for toxicological screening Du Lili and Chen Dunjin 5.
Covers all aspects of chemical warfare agent modes of action, detection, prevention, therapeutic treatment and countermeasures. Chapters cover the Keap1-Nrf2 cell defense pathway, animal models of drug-induced idiosyncratic toxicity and the use of human embryonic and induced pluripotent stem cells for modeling metabolism and toxicity. It is also of interest to laboratories engaged in stem cell research and use of stem cells for tissue regeneration, and to any organization dealing in stem cell and tissue regeneration research. Induced pluripotent stem cell-derived ocular blood-retinal barrier for disease modeling and drug discovery Jun Jeon, Nathan Hotaling, Kapil Bharti 23. Characterization and therapeutic uses of adult mesenchymal stem cells Julian Kiang 16.
Furthermore, intellectualization and proprietization of molecular pathology with respect to the discovery of new genes and or new techniques continues to pose new challenges of test ownership, legalities, liabilities, widespread acceptance and utility. Role of stem cells in the gastrointestinal tract and in the development of cancer Pengyu Huang, Bin Li, Yun-Wen Zheng 20. Now, this book reviews these procedures, discusses the science behind them, and provides real-world examples to illustrate the usefulness of the methods. Stem cells: A potential source for high throughput screening in toxicology Harish K Handral, Gopu Sriram and Tong Cao 4. It brings together world-class experts in pathology, biophysics, immunology, and stem cell research, who draw upon their extensive experience with the methods and show examples of good data to help guide researchers in the right direction.
Stem cell signaling in the heterogenous development of medulloblastoma Joanna Triscott and Sandra Dunn 22. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike. . Explores the current concepts in drug metabolism and toxicology Chapters cover such areas as the Keap1-Nrf2 cell defense pathway, animal models of drug-induced idiosyncratic toxicity and the use of human embryonic and induced pluripotent stem cells for modeling metabolism and toxicity An essential resource for pharmacologists, immunologists and biochemists alike Category: Medical. Human stem cell-derived cardiomyocyte in vitro models for cardiotoxicity screening Tracy Walker, Kate Harris, Evie Maifoshie, Khuram Chaudhary 7.
Evaluates the expansive literature, providing one resource covering all aspects of toxicology biomarkers Includes completely revised chapters, along with additional chapters on the newest developments in the field Identifies and discusses the most sensitive, accurate, unique and validated biomarkers used as indicators of exposure Covers special topics and applications of biomarkers, including chapters on molecular toxicology biomarkers, biomarker analysis for nanotoxicology, development of biomarkers for drug efficacy evaluation, and much more Category: Medical Author : Ramesh C. Divided into several key sections, this reference volume contains new chapters devoted to topics in microplastics, neuroimmunotoxicity and nutraceuticals, along with a look at the latest cutting-edge technologies used to detect biomarkers. Stem cells from human dental tissue for regenerative medicine Junjun Liu and Shangfeng Liu 25. Utilization of in vitro neurotoxicity models in pre-clinical toxicity assessment Karin Staflin, Dinah Misner, and Donna Dambach 10. Effects of Endocrine Disruptors on Mesenchymal Stem Cells Marjorie Bateman, Amy Strong, John Mc Lachlan, Matthew Burow, Bruce Bunnell 12.
This issue of Laboratory Clinics seeks to provide selective state of the art understanding of molecular pathology with respect to its relationship to key pathology disciplines as well as the current challenges and promise for the future. Comprehensively covers infectious diseases, immunotherapy, gene medicine, diagnostics, and toxicology of nanomedicine International board of authors Split into sections that cover subjects such as Nanomedicines in Immunotherapy, Nanomedicine Toxicity, and Diagnostic Nanomedicine Category: Medical Author : Martin H. Cancer stem cells: Concept, significance and management Haseeb Zubair, Shafquat Azim, Sanjeev Srivastava, Arun Bhardwaj, Saravanakumar Marimuthu, Mary Patton, Seema Singh, Ajay Singh 21. Inselman and Xi Yang 6. Features a full update on the first edition to reflect the most recent advances in the field as well as nine new chapters.
Three-dimensional culture systems and humanized liver models using hepatic stem cells for enhanced toxicity assessment Ran-Ran Zhang, Yun-Wen Zheng, Hideki Taniguch 9. Brand new chapters include a case study of the Iran-Iraq war, an overview of chemical weapons of mass destruction, explosives, ricin, the human respiratory system, alternative testing methods, brain injuries, and more. However, no resources specifically address the use of this methodology for the study of stem cells; this is especially important as stem cell analysis involves specialized methods and staining procedures based on specific characteristics such as marker expression, cell size, drug transport, and efflux of the stem cells. Given this comprehensive treatment, this book is an essential reference for anyone interested in biomarkers across the scientific and biomedical fields. Whether it pertains to carrier status of deleterious genes, diagnosis by molecular techniques, assessment of appropriate remission post treatment, parentage or forensics testing — molecular pathology continues to increase its presence and influence in the diagnostic laboratory armamentarium.
Including findings from experimental as well as clinical studies, this essential reference offers in-depth coverage of individual toxicants, target organ toxicity, major incidents, toxic effects in humans, animals and wildlife, biosensors and biomarkers, on-site and laboratory analytical methods, decontamination and detoxification procedures, and countermeasures. The problem is that once you have gotten your nifty new product, the micrornas in toxicology and medicine sahu saura c gets a brief glance, maybe a once over, but it often tends to get discarded or lost with the original packaging. Expanding on the ground-breaking first edition, Handbook of Toxicology of Chemical Warfare Agents has been completely updated, presenting the most recent advances in field. Patient diagnosis, prognosis, management and care have been influenced by molecular pathology testing algorithms on a global scale. Chapter coverage includes: Stem cell analysis and sorting using side population Flow cytometry in the study of proliferation and apoptosis Stem cell biology and application Identification and isolation of very small embryonic-like stem cells from murine and human specimens Hematopoietic stem cells—issues in enumeration Human embryonic stem cells: long-term culture and cardiovascular differentiation Limbal stem cells and corneal regeneration Flow cytometric sorting of spermatogonial stem cells Breast cancer stem cells Stem cell marker expression in cells from body cavity fluids This book is an essential resource for all graduate students, practitioners in developing countries, libraries and book repositories of universities and research institutions, and individual researchers. With an international board of authors, this volume is split into sections that cover subjects such as Nanomedicines in Immunotherapy, Nanomedicine toxicity, and Diagnostic Nanomedicine. This revised and completely updated edition includes both vertebrate and non-vertebrate species models for toxicological testing and the development of biomarkers.